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World's largest opioid review finds they often don't work

The largest review ever conducted on opioids for acute pain found that these widely prescribed drugs often deliver only small, short-lived benefits. For many common conditions, including some surgeries and kidney stone pain, opioids performed no better than a placebo. Researchers

World's largest opioid review finds they often don't work
ScienceDaily โ€” 8 June 2026
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The largest review ever conducted on opioids for acute pain found that these widely prescribed drugs often deliver only small, short-lived benefits. For many common conditions, including some surgeries and kidney stone pain, opioids performed no better than a placebo. Researchers also found higher rates of side effects and warned that dependence can begin after only a short period of use.

This report comes from ScienceDaily. The story centres on World's largest opioid review finds they often don't work. Full coverage and background context is available at the original source. Readers seeking more detail on this developing topic are encouraged to follow updates from ScienceDaily and related outlets covering this beat.

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